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2022年5月20日 星期五

地球,人間煉獄:疫情、戰爭、窮困 (274期):居隔一週。How Accurate Are Rapid COVID Tests?

 

地球,人間煉獄:疫情、戰爭、窮困 (274期):




Two testing experts explain the latest data on how well the assays perform



SCIENTIFICAMERICAN.COM
How Accurate Are Rapid COVID Tests?




居隔一週,今天出門辦事,倒也沒有恍如隔世之感。沒有到人多的地方,也沒搭大眾運輸,所以沒有特別感覺這波疫情的蕭條。
確診的頭三天最辛苦,發燒吃藥,就可退燒,但是喉嚨痛就沒什麼辦法,咳嗽不止。另外就是全身痠痛,好像做了運動一樣。這個情況到了第四天就好很多。有些人頭痛得厲害,但我沒特別疼,但是頭腦昏沉,腦筋運轉的速度慢了許多,睡得也比平常多許多,大概是身體跟這個陌生的疾病打仗,挺費力的。


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在 COVID-19 大流行的這個階段,您擔心什麼?
當我們切換到個人負責照顧自己的 COVID-19 預防模式時,我並不是 100% 相信我們已經掌握了所有信息。人們不一定意識到他們感染 COVID-19 的風險很高。

那些處於明顯高風險的人——老年人、免疫功能低下的人、未接種疫苗的人——都知道。但隨著我們對疫苗的保護減弱,有很多人因患有心髒病、高血壓或糖尿病等疾病而面臨 COVID-19 和其他疾病的高風險。這些可能在您的日常生活中得到很好的控制,但它們仍然使您更容易感染嚴重的 COVID-19。

我可以戒掉戴口罩嗎?
在冠狀病毒傳播率大大降低之前,我們需要在火車、飛機和公共汽車等地方戴上口罩。

日本使用三個 C 來提醒人們 COVID-19 風險最高的地方:封閉空間(通風受限的地方);人群;和密切接觸設置。這些是口罩提供最大益處的地方,個人應根據其風險和社區中當前的 COVID-19 數量來決定是否使用口罩。

免疫功能低下的人可能希望在大多數情況下繼續戴口罩,直到 COVID-19 發病率非常低,而健康、接種疫苗的人可能希望放棄口罩。在不再需要口罩的環境中,選擇真正具有防護性的口罩(如貼身的 KN95、KF94 或 N95 口罩)以提供最佳保護非常重要。當某個地區的病例數確實很高時,室內口罩規定可以提供最好的保護,並有助於挽救生命。另一方面,當我們達到幾乎沒有 COVID-19 傳播的程度時,除非您處於非常高的風險中,否則沒有理由戴口罩。

以後應該用什麼面膜?
根據情況和您的風險因素選擇口罩。例如,如果你是一個低風險的人,參加一個每個人都戴著口罩的活動,那麼人們不需要都穿著 N95。即使是合身的織物口罩也能提供一些保護;一個不合適的外科口罩可能也好不到哪裡去。也就是說,一個緊身面罩,比如一個帶有調整帶的手術面罩,如 KN95s 和 KF94s,將是一個真正的進步。一個合適的 N95 面罩是最好的。

我應該多久洗手或消毒一次?
對於在表面上傳播的感冒,洗手是至關重要的;對於其他感冒,您只會從空氣中的咳嗽和打噴嚏中感染它們。但是當你在他們身邊時,你不會知道他們患的是哪種感冒。每當我切換設置或更改建築物時,我都喜歡洗手。比如我下班回家,一路上摸了很多東西,所以我一到家就洗手。還要確保在準備食物、進食和使用洗手間後洗手。

“每個人都需要接種 COVID-19 疫苗,並且跟上助推器也是明智之舉。”
—副教授。 Emily Landon 教授
—副教授。 Emily Landon 教授 — 副教授。 Emily Landon 教授
在大流行期間,流感幾乎消失了。我應該打流感疫苗嗎?
我不認為如果我們要求每個人都戴口罩,就可以徹底結束流感。但在正常年份,數以萬計的美國人死於流感。我們傾向於低估流感和其他呼吸道病毒,因為當我們年輕健康時,它們看起來就像是嚴重的、令人討厭的感冒。但它們可能會危及某些人的生命,包括兒童甚至一些健康的成年人。流感疫苗有助於預防住院、肺炎甚至死亡等不良後果。儘管如此,您不應該依賴疫苗作為您唯一的保護層。生病時,您還需要洗手並待在家裡。如果您是高風險人群,請確保您可以使用達菲等藥物。

在接下來的幾個月裡,老年人和/或免疫功能低下的人應該如何應對?
高危人群可能需要採取更多預防措施,因為其他人不再戴口罩來幫助保護他們。例如,在與其他人在一起的封閉空間中,風險最高的人可能需要同時佩戴 N95 和麵罩,以保護他們的眼睛免受大的 COVID-19 飛沫的傷害。如果無法與未戴口罩的人保持 6 英尺的距離,風險最高的人也可能需要完全避開人群,即使是在外面也是如此。由於疫苗對這一群體沒有那麼有效,因此請務必遵守疫苗接種建議並註意 COVID-19 的情況。您的醫生應該能夠說出新的建議是否適用於您。

在這一點上,為什麼還要接種 COVID-19 疫苗呢?
每個人都需要接種 COVID-19 疫苗,並且跟上助推器也是明智之舉。未接種疫苗的人死於 COVID-19 的可能性是接種疫苗的人的 10 倍。目前的建議是安全的

What worries you at this stage of the COVID-19 pandemic?

As we switch to a COVID-19 prevention model where individuals are responsible for taking care of themselves, I’m not 100% convinced we've gotten all of the information out. People don’t necessarily realize they’re at high risk for getting a bad case of COVID-19.

Those at obvious high-risk—older individuals, the immunocompromised, the unvaccinated—know. But as protection from our vaccines weaken, there are a lot of people who are at high risk for COVID-19 and other conditions because they have illnesses like heart disease, high blood pressure or diabetes. These may be well-controlled in your day-to-day life, but they still make you more vulnerable for severe COVID-19.

Can I quit wearing a mask?

Until coronavirus transmission is much lower, we need to keep masks on in places like trains, planes and buses.

Japan uses the three C’s to remind people where risk of COVID-19 is highest: closed spaces (places with limited ventilation); crowds; and close contact settings. These are the places where masks offer the best benefit and individuals should decide whether or not to use a mask based on their risk and the current amount of COVID-19 in the community. 

Immunocompromised folks may want to keep wearing masks in most of these settings until COVID-19 rates are very low, whereas healthy, vaccinated people may want to forgo a mask. In a setting where masks aren’t required anymore, it’s important to choose a really protective mask (like a close-fitting KN95, KF94 or N95 mask) to provide the best protection. When cases are really high in an area, indoor mask mandates provide the best protection and can help save lives. On the other hand, when we get to a point where there’s almost no COVID-19 circulating, there’s no reason to be wearing masks unless you’re at very high risk.

What mask should I use in the future?

Choose the mask based on the situation and your risk factors. For instance, if you're a low-risk individual going to an event where everybody's wearing masks, people don't need to all be in N95s. Even a well-fitting fabric mask will offer some protection; a poorly fitting surgical mask probably isn’t any better. That said, a tight-fitting mask, like a well-fitted surgical mask with adjusted straps, such as KN95s and KF94s, would be a real step up. A fitted N95 mask is best.

How often should I be washing or sanitizing my hands?

For colds that are spread on surfaces, washing your hands is critical; for other colds, you're only going to pick them up from coughs and sneezes in the air. But you're not going to know what type of cold someone has when you're around them. Any time I switch settings or change buildings, I like to wash my hands. For example, when I go from work to home, I’m touching a lot of stuff along the way, so I wash my hands when I get home. Also make sure to wash your hands before preparing food, eating and after using the washroom.

“Everyone needs to be vaccinated for COVID-19 and it’s wise to keep up with boosters as well.”
—Assoc. Prof. Emily Landon

大流行響起,流感幾乎消失了。我應該打流感疫苗嗎?

我不認為如果我們要求每個人都戴口罩,就可以徹底結束流感。但在正常年份,數以萬計的美國人死於流感。我們傾向於低估流感和其他呼吸道病毒,因為當我們年輕健康時,它們看起來就像是嚴重的、令人討厭的感冒。但它們可能會危及某些人的生命,包括兒童甚至一些健康的成年人。流感疫苗有助於預防住院、肺炎甚至死亡等不良後果。儘管如此,您不應該依賴疫苗作為您唯一的保護層。生病時,您還需要洗手並待在家裡。如果您是高風險人群,請確保您可以使用達菲等藥物。


在接下來的幾個月裡,老年人和/或免疫功能低下的人應該如何應對?

高危人群可能需要採取更多預防措施,因為其他人不再戴口罩來幫助保護他們。例如,在與其他人在一起的封閉空間中,風險最高的人可能需要同時佩戴 N95 和麵罩,以保護他們的眼睛免受大的 COVID-19 飛沫的傷害。如果無法與未戴口罩的人保持 6 英尺的距離,風險最高的人也可能需要完全避開人群,即使是在外面也是如此。由於疫苗對這一群體沒有那麼有效,因此請務必遵守疫苗接種建議並註意 COVID-19 的情況。您的醫生應該能夠說出新的建議是否適用於您。


在這一點上,為什麼還要接種 COVID-19 疫苗呢?

每個人都需要接種 COVID-19 疫苗,並且跟上助推器也是明智之舉。未接種疫苗的人死於 COVID-19 的可能性是接種疫苗的人的 10 倍。目前關於不戴口罩和“恢復正常”是安全的建議適用於接種疫苗的人。即使是健康的未接種疫苗的人在感染 COVID-19 後也面臨著不良後果的高風險。這些疫苗的接種劑量幾乎比其他任何疫苗都多,接種疫苗的人表現很好。我們沒有看到人們死亡或出現與疫苗有關的醫療問題。另一方面,未接種疫苗的 COVID-19 感染已導致數十萬美國人死亡,並導致數百萬例長期 COVID、中風、心髒病發作、腎衰竭、心力衰竭、肺損傷、血栓……這個名單還在繼續。 .

During the pandemic, the flu all but disappeared. Should I bother with a flu vaccine?

I didn't think that if we asked everybody to wear a mask, it would completely end influenza. But in a normal year, tens of thousands of Americans die of influenza. We tend to underappreciate influenza and other respiratory viruses, because when we’re young and healthy, they just seem like bad, nuisance colds. But they can be life-threatening for some people, including kids and even some healthy adults. The flu vaccine is helpful in preventing bad outcomes like hospitalization, pneumonia and even death. Still, you shouldn’t rely on the vaccine to be your only layer of protection. You also need to wash your hands and stay home when you’re sick. And if you’re high-risk, make sure you have access to medications like Tamiflu.

How should people who are older and/or immunocompromised navigate the next few months?

High-risk individuals may need to take more precautions because others are no longer wearing masks to help shield them. For instance, in closed spaces with other people, the highest-risk individuals may need to wear both an N95 and face shield to protect their eyes from large COVID-19 droplets. Highest-risk people probably also need to avoid crowds altogether, even outside, if they can’t keep 6 feet of distance from the unmasked. Because vaccines aren’t as effective for this group, make sure to keep up with vaccination recommendations and pay attention to the COVID-19 situation. Your physician should be able to say whether new recommendations apply to you.

At this point, why bother getting vaccinated against COVID-19?

Everyone needs to be vaccinated for COVID-19 and it’s wise to keep up with boosters as well. Individuals who are unvaccinated are 10 times more likely to die of COVID-19 than the vaccinated. The current recommendations that it’s safe to be unmasked and "get back to normal" is meant for vaccinated people. Even healthy unvaccinated people are at high risk of a bad outcome after having COVID-19. More doses of these vaccines have been given than almost any other vaccine and vaccinated people are doing beautifully. We are not seeing people die or have medical problems related to the vaccine. Unvaccinated COVID-19 infection, on the other hand, has killed hundreds of thousands of Americans and caused millions of cases of long COVID, strokes, heart attacks, kidney failure, heart failure, lung damage, blood clots… the list goes on and on.

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