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2021年4月15日 星期四

地球,人間煉獄 C (100th、一百期) :氣喘藥對治療Covid 有效;富國該捐多餘疫苗。法國Covid死亡超過 100,000人。印度單日新增病例屢創新高。CureVac的"希望".。.輝瑞CEO:可能每年都需注射新冠疫苗加強針....

 Top officials from the UN, the World Bank and the GVA urge rich countries to donate excess COVID-19 vaccine doses to help supply low- and middle-income countries.

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Inhaled asthma drug shortens Covid recovery and could be ‘significant for world,’ study finds

An inhaled drug commonly used for asthma has been shown to shorten the recovery time of Covid-19 sufferers who do not need hospital treatment – a development that has been described as a “significant milestone” in the fight against coronavirus.

British scientists from Oxford University have found that budesonide, an anti-inflammatory medicine, can help accelerate recovery in the over-50s by an average of three days.

The readily available drug, administered via a cheap

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印度第二波武漢肺炎疫情單日新增病例屢創新高,15日新增20萬例確診,有1038人死亡。新德里也將23家飯店和婚宴埸所,改裝為醫院的新冠疫情治療中心,以增加2千多張床位。

India has recorded more than 200,000 new coronavirus infections in a single day as hospitals report severe shortages of beds and oxygen and extra space is found in hotels

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法国自新冠疫情爆发以来累计死亡病例突破10万大关;法国总统马克龙周四发推文表示,"我们将不会忘记每张面孔,每个名字"。马克龙周四晚召集政府官员举行会议,讨论法国逐步解封计划。

The country is on the cusp of having administered 200m jabs.


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荷、德合作的新疫苗:CureVac NV is some five months behind the front-runner messenger RNA vaccines against Covid-19. But after the industry’s recent setbacks, that’s starting to look like good timing.

キュアバック (CureVac)

会社

内容

説明

英語から翻訳-CureVac N.V.は、オランダに合法的に居住し、ドイツのテュービンゲンに本社を置くドイツのバイオ医薬品企業であり、メッセンジャーRNAに基づく治療法を開発しています。同社は、感染症のワクチンや、がんや希少疾患を治療するための薬の開発に注力しています。 ウィキペディア(英語)


由於 Johnson & Johnson漢 第二波武漢肺炎疫情單日新增病例屢創新高,15日新增20萬例確診,有1038人死亡。新德里也將23家飯店和婚宴埸所,改裝為醫院的新冠疫情治療中心,以增加2千多張床位。




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法国自新冠疫情爆发以来累计死亡病例突破10万大关;法国总统马克龙周四发推文表示,"我们将不会忘记每张面孔,每个名字"。马克龙周四晚召集政府官员举行会议,讨论法国逐步解封计划。


The country is on the cusp of having administered 200m jabs.

FT.COM

Coronavirus latest: French Covid death toll exceeds 100,000

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輝瑞CEO:可能每年都需注射新冠疫苗加強針

輝瑞公司首席執行官Albert Bourla表示,人們在接種新冠疫苗后的一年內可能將需要注射加強針,然後每年都要接種新冠疫苗,以維持人體對新冠病毒的預防能力。

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研究發現新冠患者出現嚴重血栓的風險大於疫苗接種者

牛津大學的一項研究發現,新冠患者出現罕見但有時是致命的血栓的風險,大約是接種過廣泛使用的西方開發的前三種疫苗中任何一種的人的8至10倍。

由於 Johnson & Johnson與 AstraZeneca 都用同一技術,都有百萬分之一雞會引發接踵者血栓之風險......

所以 Pfizer-BioNTech and Moderna 兩疫苗採用 m-RNA技術者或較可靠:


荷、德合作的新疫苗:CureVac NV is some five months behind the front-runner messenger RNA vaccines against Covid-19. But after the industry’s recent setbacks, that’s starting to look like good timing.


キュアバック (CureVac)

内容

説明英語から翻訳-CureVac N.V.は、オランダに合法的に居住し、ドイツのテュービンゲンに本社を置くドイツのバイオ医薬品企業であり、メッセンジャーRNAに基づく治療法を開発しています。同社は、感染症のワクチンや、がんや希少疾患を治療するための薬の開発に注力しています。 ウィキペディア(英語)



The Oxford-AstraZeneca vaccine is based on the virus’s genetic instructions for building the spike protein. But unlike the Pfizer-BioNTech and Moderna vaccines, which store the instructions in single-stranded RNA, the Oxford vaccine uses double-stranded DNA.

DNA Inside an Adenovirus

The researchers added the gene for the coronavirus spike protein to another virus called an adenovirus. Adenoviruses are common viruses that typically cause colds or flu-like symptoms. The Oxford-AstraZeneca team used a modified version of a chimpanzee adenovirus, known as ChAdOx1. It can enter cells, but it can’t replicate inside them.

DNA inside

an adenovirus

AZD1222 comes out of decades of research on adenovirus-based vaccines. In July, the first one was approved for general use — a vaccine for Ebola, made by Johnson & Johnson. Advanced clinical trials are underway for other diseases, including H.I.V. and Zika.

The Oxford-AstraZeneca vaccine for Covid-19 is more rugged than the mRNA vaccines from Pfizer and Moderna. DNA is not as fragile as RNA, and the adenovirus’s tough protein coat helps protect the genetic material inside. As a result, the Oxford vaccine doesn’t have to stay frozen. The vaccine is expected to last for at least six months when refrigerated at 38–46°F (2–8°C)....



The risk of developing a serious brain clot is 8 to 10 times higher in people with Covid than those who get a vaccine, a study has suggested.

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